Once someone is vaccinated, do they still have to wear a mask? Your COVID-19 vaccine questions answered

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Now that a COVID-19 vaccine has been approved in Canada and the first shotshave been given, lots of you have questions about vaccines: If I've previously tested positive for COVID-19, should I still get vaccinated? Is the vaccine safe for pregnant women, children and people who are immunocompromised?Where can I find the ingredients list?Can I choose which vaccine to get? We talked to the experts to get you some answers.

Oncesomeone isvaccinated, do theystill have to wear a maskand physically distance?

Dr. Zain Chagla, an associate professor of medicine at McMaster University and an infectious disease physician in Hamilton, Ont., said yes, in the short-term, for two reasons.

The first is, during such a large immunization, not everyone will get vaccinated at the same time. Some will be vaccinated while others are still waiting and need to be protected by wearingmasks, physical distancing, frequent hand-washingand other safety measures.

"Plus, it takes time for the immune response to actually build up and kick in," Chagla said.

WATCH | How we'll learn more about the effectiveness of the vaccine over time:

Dr. Sharma is asked how long the Pfizer vaccine is effective against COVID

4 years ago

Duration 2:06

Health Canada chief medical adviser Dr. Supriya Sharma spoke with the CBC's Tom Parry during a briefing on Wednesday.

Given that the vaccines will be rolled out in a step-wise fashion starting with the most vulnerable populations, the health-care workers who serve them and then scaling up to the general public, Dr. Tasleem Nimjee, an emergency department physician in Toronto, suspects thatwe'll see a parallel drawing back on public health measures such as wearing masks and staying apart.

"It's not going to be a sort of, 'Now we can all take off our masks,'"Nimjee said on The National's virtual town hall, Confronting COVID.

Instead, shedding masks will likely be more gradual.

Can you still carry and spread the virus if you've been vaccinated?

That's not something most of the clinical trials were designed to test, said Dr. Michael Gardam, a Toronto infectious disease physician who is currently the senior medical adviser for Health PEI.

In the recently published study on the clinical trial results for the AstraZeneca vaccine, the efficacy against asymptomatic infection was just 27 per cent suggesting those vaccinated generally can still transmit the disease but the number of cases was quite small to draw conclusions.

WATCH | Why vigilance and patience will still be required in 2021:

Hold on and stay safe while vaccinations begin: WHO

4 years ago

Duration 1:48

As vaccinations get underway, the World Health Organization's technical lead, Maria Van Kerkhove, makes an impassioned appeal for people to protect themselves and loved ones from COVID-19 in 2021.

Moderna says it does plan to check if its vaccine prevents morethan just symptomatic infection.

Gardam said because it's something that still needs to be figured out, "for now, getting vaccinated does not automatically mean that you couldn't potentially pass COVID-19 on to someone else."

That's another reason he expects we'll be wearing masks for a while, he said.

Will those who have tested positive for COVIDget the vaccine or will they be deemed to have immunity? Is there any danger if they do get the vaccine?

There's not enough information yet to answer the firstquestion, said Dr. Isaac Bogoch, an infectious disease doctor in Toronto and a member of Ontario's COVID-19 vaccine distribution task force.

"But my inkling," he said,"is that they should be vaccinated."

Bogochsaidthere have been reports of people getting reinfected with COVID-19 as soon as four months after recovering from their previous infection, and those are probably the tip of the iceberg. He said he expects most people who have recovered from COVID-19 will be eligible for vaccination.

As to whether getting the vaccine poses a risk to those who have been previously infected, Gardam said no, there is no danger.

He said vaccines are routinely given to people without testing if they have been exposed to the disease, because it's logistically easier to just vaccinate everyone.

Can a person that has an active case of COVID-19 get the vaccine, and will it be effective while they are ill?

People with active COVID-19 infections should be self-isolating, so they shouldn't be going to get a vaccination.Generally, patients are screened for symptoms of illnessbefore any vaccination, and vaccinations are postponed if you are sick.

But even if you somehow can get a COVID-19 vaccine while sick, you shouldn't,because the coronavirus that causes it canimpact the way your immune system functions, suggests Jason Kindrachuk, Canada Research Chair in Emerging Viruses at the University of Manitoba.

"This virus operates by really playing a tricky gamewith our immune system during the course of the disease," he told CBC News Network.

"That of course is a concern for us because we don't want to see someone being vaccinated when their immune system isn't quite ready yet to take that vaccine."

He recommends waiting until you're well into recovery.

What if only half the population is vaccinated? How much of the population has to be vaccinated to achieve herd immunity?

Herd immunity is the point at which the viruscan't find enough people to infect in order to continue the chain of infection.

Vaccinating half the population probably won't be enough.

The percentage required to achieve herd immunity depends on how many people a single infected person spreads the disease to on average. For COVID-19, this is thought to be between twoand three, soabout 60 to 70 per cent of the population will need to be immune in order to achieve herd immunity.

WATCH | What to expect with the vaccine rollout:

Health Canada's approval of Pfizer vaccine a 'historic moment'

4 years ago

Duration 6:00

Infectious diseases specialist Dr. Sumon Chakrabarti says Health Canada's approval of the Pfizer-BioNTech COVID-19 vaccine is a 'historic moment' that will trigger the first wave of a countrywide immunization campaign.

In other words, if a vaccine is 100 per cent effective, then 60 to 70 per cent of the population would need to be vaccinated.

However, the COVID-19 vaccineshave been less than 100 per cent effective in clinical trials, and may be even less so in the real world, saidDr. Zain Chaglaof McMaster University. That's because the trials didn't include people with certain medical conditions, such ascancer, or transplant recipients, to name a couple examples.

So, how effective are the vaccines when they're given to all kinds of people?

"That's really what's going to determine how long it takes to get to true herd immunity," Chagla said.

Will the Pfizer-BioNTech and Moderna vaccines work for people on chemo or suffering from autoimmune diseases or taking an immunosuppressant drug? Will they be able to take these vaccines?

Bogoch said those conditions are all different, and it's important for anyone who has them to talk to their doctor about their unique situation.

"But, in general, it's very likely that those with an immunocompromised state will be eligible for this vaccine," he said.

It's possible that they won't generate the same level of immunity as a healthy person, he said, "but some protection is better than nothing."

Gardamsaidthere may be concerns about giving a vaccine containing live viruses to an immunocompromised patient, but the Pfizer-BioNTech and Moderna vaccines contain only genetic material.

"There's nothing live in that. So, typically, people who are immunocompromised can get vaccines like that."

Could a person get a shot of the Pfizer-BioNTech vaccine for their first doseand theModerna vaccine for their second?

Right now, you can't take shots of two different vaccines, BogochtoldCBC News Network.

"If you start with Moderna, you end with Moderna," he said."I doubt anything would happen if you mixed and matched, but it's not going to happen. You shouldn't be doing that."

That's because different vaccines haven't been tested together yet. However, tests of combinations of different types of COVID-19vaccineshave been proposed fornext year, so that could change in the future.

Can I choose one vaccine overanother?

"I suspect we won't have the luxury of doing that, at least in the early stages," said Dr. Susy Hota, an infectious disease specialist at the University Health Network and an assistant professor of medicine at the University of Toronto.

Quantities of the vaccine will be limited for now.

"We'll probably have to get whatever's available at that time," she said.

WATCH | COVID-19 vaccinations off to a quick start in the U.K.:

U.K. vaccinates thousands against COVID-19 on 1st day

4 years ago

Duration 3:10

Thousands of people across the U.K. received the first doses of the Pfizer COVID-19 vaccine on Tuesday, but officials are warning there is still a long way to go before the end of the pandemic.

Where can I find a list of ingredients for the Pfizer-BioNTech vaccine?

The ingredients are listed on Page 23 of the vaccine's product monograph. A detailed article about them was recently published in theMIT Technology Review.

In general, you can find the ingredients list for vaccines in theCanadian Immunization Guideor the vaccine's product monograph available throughHealth Canada's Drug Product Database.

Do I still need to take the flu shot if I get the COVID-19 vaccine?

Absolutely, Chagla says.

The reason is, the flu andCOVID-19are caused by different viruses and need different vaccines.

"The time is probably now to get your flu shot in," Chagla said.

Will we need to take this vaccine yearly like the flu shot?

Dr. Lynora Saxinger, an infectious disease physician at the University of Alberta, said we don'thave an answer yet because immune responses to the vaccines haven'tbeen studiedlong enough to know.

Gardam said there's been a lot of discussion about whether vaccines to protect against COVID-19 will be needed each year.

"The only way we're going to know that is by following people along over the next nine months to a year to see if they still have good immunity or not," Gardam said.

I suffer from severe trypanophobia. Is there an oral or nasalCOVID-19 vaccine in the works?

Trypanophobia is fear of medical procedures involving injections or needles. Those who suffer from it will be happy to know thata number of oral and nasal COVID-19 vaccines are indevelopment. Infact, there are research groups in Canada working to develop both those kinds of vaccines, and the oral vaccine from Symvivo has begun clinical trials. There is also a nasal spray from Beijing Wantai Biological Pharmacy and Xiamen University that is in Phase 2 clinical trials, according to the World Health Organization's tracker.

What constitutes a 'history of serious allergic reactions?' Once?

Anaphylaxis is a serious allergic response by the body to a substance in a food, medicine or vaccine.

Chagla said people with anaphylaxis can get very short of breath and their blood pressure can drop.

The experience of a single episode that required epinephrine,such as from anEpiPen or other auto-injector, constitutes a "history of serious allergic reaction."

WATCH | Investigating adverse events after vaccinations:

U.K. regulators warn of possible Pfizer vaccine allergies

4 years ago

Duration 4:44

British regulators say people who have a 'significant history' of allergic reactions shouldn't receive the new Pfizer-BioNTech coronavirus vaccine. Two adverse reactions occurred on the first day of the country's mass vaccination program.

Dr. Zainab Abdurrahman of McMaster University's clinical immunology and allergy departmentsaid the U.K. regulators temporarily paused delivery of the Pfizer-BioNtech vaccine to people with a history of anaphylaxis after two adverse events occurred among health-care workers with such a history who carried auto-injectors.

Both received the vaccine and then experienced reactions that doctors and regulators call adverse events until any cause-and-effect relationships are sorted out.The two peoplewere treated immediately and recovered without needing to be hospitalized.

"There's a lot of different kinds of reactions and we need to clarify exactly what happened," such as what components of the vaccine might be responsible,Abdurrahman said.

The adverse events could becoincidences that weren't caused by the vaccinations. The events are under investigation and further guidance could come from regulators, Chagla said.

WATCH |Clinical allergist answers key questions about vaccine:

Clinical allergist answers key questions about vaccine

4 years ago

Duration 7:29

Dr. Zainab Abdurrahman, a clinical immunologist and allergist, says only one ingredient in the Pfizer-BioNTech COVID-19 vaccine has been known to cause allergic reactions in the past. And the ingredient, polyethylene glycol, is already widely used. The other ingredients are not known to cause allergy.

How many vaccines can our bodiestolerate?

Dr. Noni MacDonald, a professor of pediatrics at Dalhousie University who specializes in vaccine safety and communication, said she's been getting this question for at least 25 years. Vaccines contain antigens generally viruses, bacteria or parts of them that trigger an immune response similar to those triggered by the microbes themselves.

"I think what people don'tknow is how much we are bombarded by antigens every day," MacDonald said. Those include the microbes in your gut, in your food, in the air you breathe. "The amount of antigens that are in these vaccines is extraordinarily limited."

And such small amounts are not going to overwhelm your immune system, shesaid.

And asChagla points out, our bodies are programmed to deal with multiple pathogens and immune triggers at the same time.

"In everyday life, it's not like every bacteria and virus takes a break because one other bacteria and virus has affected you. You can get a cold and then eat something that gives you food poisoning."

In fact, infants receive a number of vaccines in a single product.

"We're able to take multiple vaccines," Chagla said.

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