Memorable Golden Globes moments: Oprah's power, history-making wins and Seth lets loose

Women led the way at an unusually political Golden GlobeAwards in Beverly Hills, Calif., Sunday night, as Hollywood's highest-profilepost-HarveyWeinsteinawards show so far turned the spotlight largely towardfemale-focusedstories andactors declaring,"Time's up."

In a fast-paced evening celebrating the past year in U.S. film and television, here are somemoments and trends that stood out.

Thepower of Oprah

A host of winning actors delivered strong statements addressing the #MeToomovement and decrying the culture of misconduct in Hollywood and beyond, fromBig Little Lie's LauraDernandReeseWitherspoon,The Handmaid's Tale's Elisabeth MossandThree Billboards Outside Ebbing, Missouri's FrancesMcDormand.

But leave it toOprah Winfrey broadcasting mogul and the Hollywood Foreign Press Association's first black female Cecil B.DeMilleAward-winner tocrystalizethis cultural moment into a moving and emotional speech that garnered multiple standing ovations from the audience and accolades across social media.

With her signature brand of personal tale-meets-inspirational oratory,Winfrey drew together threads about the American civil rights movement, the current backlash against sexual misconduct as well as the importance of the press in anamped-upspeech that reached beyond those in the room to those watching at home.

A different kind of red carpet couple

A host of top actors helped flip the often inane red-carpet gauntlet on its head by turning up accompanied by notable activists working on social justice issues, from Me Too founderTaranaBurke alongside Michelle Williams, to pro tennis player Billie Jean King with Emma Stone.

Others likeSalmaHayek and Ashley Judd, Sarah Paulson and AmandaPeet, and AmericaFerreraand NataliePortman chose to attend with a female friend as their "date" for the night.

"We're used to being the only women in the workplace.We're used to being one-at-a-time players and we realize how much louder and stronger our voices can be when we come together,"Portmannoted on the red carpet.

SethMeyers'sopener

Newbie Globes host SethMeyersgamely went after the "elephant not in the room" by diving right into jokes about disgraced producerWeinsteinand the myriad sexual misconduct scandals roiling the entertainment business.

While the room had mixed reactions to some jokes, many on social media cheered on the late-night host for not pulling his punches:Kevin Spacey, HBO and Woody Allen were just a few he called out in his monologue.

Lady Birdwins

Greta Gerwig accepted the trophy for the film Lady Bird in the best musical or comedy category. The film was her directorial debut and the year's most widely acclaimed film.

The poignancy of that win wasn't lost on many, including presentersPortmanwho bluntly pointed out the all-male list of film director nominees when announcing that category and Hollywood icon Barbra Streisand, who balked at the part of her introduction that described her as the Globes' only female film director winner (for 1984'sYentl) thus far.

History in the making

In an evening dominated by women, two men shared the spotlight with milestone Golden Globe wins.AzizAnsaribecame the first Asian-American winner of best lead actor in a TV comedy, while Sterling K. Brown became the first African-American winner of best lead actor in a TV drama.

"You wrote a role for a black man. That could only be played by a black man," Brown said in his acceptance speech, addressingThis Is Uscreator Dan Fogelman.

"WhatI appreciate so much about this thing is that I've been seen for who I am and being appreciated for who I am. And it makes it that much more difficult to dismiss me, or dismiss anybody who looks like me."