The Big Bang Theory to end in 2019 after 12 seasons

CBS says the upcoming 12th season of The Big Bang Theorywill be the last.

It's the most popular comedy on television.

Featuringa theme song by Canadian groupBarenakedLadies,the hit series revolves around geeky physicist roommates portrayed by Jim Parsons and Johnny Galecki and their best friends andgirlfriends (who eventually become their wives). Other stars include KunalNayyar,KaleyCuoco, SimonHelberg, Melissa Rauchand MayimBialik.

Over the years, the show has been graced with a long list of notable guest stars, including astronauts Buzz Aldrin and Mike Massimino, physicist Stephen Hawking, Tesla founder ElonMusk, science host Bill Nye andStar Trek's Leonard Nimoy, George Takei,LeVarBurton and WilWheaton.

Parsons' work on the show has earned him four Emmy awards and a Golden Globe.

CBS also airs a prequel about his character called Young Sheldon.

There's also a UCLA scholarship created by and named for the series to support undergrad study in science, technology, engineering and math (STEM).

Season 12 of Big Bangpremieres Sept. 24.