'Treated like lab rats': malaria drug's dark side-effects haunt Canadian vets

Greg Janes was one of 900 members of the Canadian Airborne Regiment who went to Somalia in 1992 as part of a peacekeeping mission. As a medic, one of his jobs was to make sure everyone took the anti-malaria medication mefloquine.

Janessaid soldiers were not asked for their consent before being administered the drug,even though it was considered experimental at the time.

I don't remember anything about side-effects being mentioned.-Greg Janes, veteran

"It was never a question of having a choice to take it or not to take it ...Idon't remember anything about side-effects being mentioned," said Janes, who lives in Orlans and now works as a police officer.

The soldiers, including Janes, took weekly doses of the drug on Tuesdays, and soon began referring to the ritual as "Psycho Tuesdays,"and to the nightmarish side effects they began suffering as "meflomares."

"I, and certainly the ones I'm in contact with, have never really been able to come out of that state of mind,"Janessaid. "How does that translate to civilian life? Not very well."

In addition to the nightmares, Janes said hissymptoms included chronic insomnia, hypervigilance, irritability and "hair trigger" aggressiveness.

Mission endedin scandal

The mission ended in scandal after two Canadian soldiers were charged with torturing and beating to death a Somali teenager. At an inquiry that followed, questions were raised about whether mefloquine may have played a role in the soldiers'violent crimes.

Manysoldiers now say they started experiencing psychological problems soon after taking the drug in Somalia and that those problems persistedlong after they returned to Canada.

Since his return to Canada in 1993, Janes said he's sufferedfrom post-traumatic stress disorder, or PTSD, but he believes some of his lingering psychological problems can be traced backto mefloquine.

"Why is it after a quarter-century of medication and psychological counselling most if not all of us cannot make the transition back? Could it be were poisoned? The possibility exists," Janes said. "Idon't think that that's normal, and I'm not alone here."

Other veterans speak out

This fall the StandingCommitteeon Veterans Affairs held two days of hearingswhere MPs listenedto a handful ofveterans describe how they believe mefloquinehas adversely affected them.

The committee has also received dozens of emailsand phone calls in the past few weeks. As well as veterans who served inSomalia, soldiers who took mefloquine while stationed in Rwanda and Afghanistan have contacted the committee to say they, too,have suffered psychological problems as a result of taking the drug.

Conservative MP CathayWagantallis a member of the committee. She saidveterans have similar stories of insomnia, anxiety, paranoia and depression.

"Mefloquine was given to them when they were in Somalia as an experimental drug. It wasn't licensed, yet there were protocols that were supposed to be followed to make sure they were screened, to make sure they should take it, and then followup throughout and none of that happened. So no information went back to the drug company or Health Canada," Wagantall said.

Health Canada, drug supplier issue warnings

In recent yearsHealth Canada has advised people with pre-existing mental health issuesincluding depression, general anxiety, schizophrenia andpsychosis, as well as anyone with a history of convulsions,not to take the drug.

In August, AA Pharma, the drug's Canadian supplier, releaseda statement warning "psychiatric symptoms ranging from anxiety, paranoia and depression to hallucinations and psychotic behaviorcan occur with mefloquine use. Symptoms may occur early in the course of mefloquine use and on occasion, these symptoms have been reported to continue long after mefloquine has been stopped."

AA Pharmaclaims the incidenceof serious adverse psychiatric reaction is just one in 11,000.

MP calls for comprehensive study

Wagantall disputes that figure, and said in the last month alone she's heard from more than a dozenveterans who've suffered serious reactions that could be linked to the drug. She's calling for a comprehensive study of all veterans who took the drug.

'Ijust hope they find the need to come forward and say, 'Look, we were treated like lab rats.You did an experiment on us and nowyou need to be honest about this whole thing.'"- Greg Janes, veteran

"We want to find out who all these individuals are, track them, find out what has happened as far as side-effects for them ... and have it recognized that this needs to be treated specifically as a different type of injury, Wagantall said."When you try to treat it as though it's PTSD,it causes all kinds of other complications."

Janesblamesthe drug for a failed marriage and lost friendships, and said it has adversely affected his career, first as a solider and then a police officer. He'sno longer on patrol, and has taken a desk job.

He continues to suffer from insomnia, getting by on three or four hours of sleep a night.

"For what it's cost me personally, for what it's cost me professionally, both in the military and as a police officer, I think I would have taken my chances with malaria," Janes said.

Janes said he decided to tell his storywiththe hopethat it will inspireother veterans to reach out for help.

"Ijust hope they find the need to come forward and say, 'Look, we were treated like lab rats.You did an experiment on us and nowyou need to be honest about this whole thing," he

"Let's not wait till we're all dead before families get to hear an apology. An acknowledgement and an apology, and they need to make it right."