I got AstraZeneca now what? Answers to questions Manitobans might have

Is AstraZenecastill safe? Has it been safe all along? Is there enough kicking around in Manitoba for me to get my second dose?

Short answers: yes, yes and maybe not.

Manitobans who have already received a jab of the AstraZeneca-Oxford vaccine may have a few questions after learning that generally, no more first doses of thatvaccine will be offered in the province.

The medical lead of the provincial vaccine campaign made that announcement on Wednesday, citing both supply chain issues and safety concerns.

"AstraZeneca has had a bit of a bumpy road with its rollout," Dr. Joss Reimer said during a Wednesday news conference. "I know Manitobans have seen different advice coming from different players."

First,a look at the supply issue.

Supply was disrupted beginning in Marchamid skyrocketing COVID-19 cases in India. The Serum Institute of India, whichproduces a biologically identical version of the AstraZeneca product called Covishield, has been blocked from shipping its product overseas.

AstraZeneca makes up a small portion of vaccines received by Manitoba84,260 of the730,230 vaccine doses shipped to the province so far.

Manitoba has about7,000 AstraZeneca dosesleft, and a shipment of about 23,000 is expected in the coming weeks.

After that, there are no assurances of when the next batch could arrive.

Mix and match

Sowhere does that leave the over 75,000 Manitobans who have already received an AstraZeneca shot?

Reimer said most remaining doses will earmarked to give those people theirsecondAstraZeneca shot. Some may get something else.

Manitoba is expecting hundreds of thousands of doses, primarily of Pfizer-BioNTech, but also someModerna, in the coming weeks.

That robust supplyis one reasonthose who received an AstraZenecafirst dose might getModerna or Pfizer for the second, said Reimer.

"I was pleased to get and I would be pleased to have another shot of AstraZeneca," said Adele Perry, who lept at the opportunity to get a dosein April.

"I am also open to hearing the new information that's coming about combining different kinds of COVID-19 vaccine."

Provinces are eyeing a clinical trial in the U.K. on the efficacy and protection offered when mixing andmatching mRNA-basedvaccines, such as Pfizer and Moderna, with something like AstraZeneca, which uses a viral vector technology.

Early results from that trial were released Wednesday, but more results on theoverall safety or effectiveness of mixing vaccines are expected in the coming weeks.

Still safe, still effective: Reimer

Now, the safety piece.

Health Canadaapproved AstraZeneca for emergency use earlier this year. It's beenapproved by other countries, then paused, then approved for some ages, then paused for others.

Manitobans 40 and up, or those 30 and older with health conditions, have been eligible for anAstraZeneca shot for weeks at doctors' offices and pharmacies.

Four provinces, including Manitoba, decided this weekto suspend their AstraZeneca campaigns or reserve future doses for those who received that shot as a first dose.

WATCH |Manitoba stands by AstraZeneca amid new eligibility restrictions, Reimer says:

Manitoba vaccine official stands by AstraZeneca amid new eligibility restrictions

3 years ago

Duration 3:53

Dr. Joss Reimer, medical lead of Manitoba's vaccine task force, on Wednesday commended those who got their first shot of AstraZeneca. She said the vaccine remains safe and effective, and its benefits outweigh any rare risks associated with the vaccine.

Alberta and Saskatchewancited supply chain issues in their decision, whileOntario suggested it's beginning to see an uptick in rare but serious blood clots associated with AstraZeneca, known asvaccine-induced immune thrombotic thrombocytopenia (VITT).

Most of thestopping and restarting abroad has been over concerns about VITT.

The current evidence suggests the risks of developing the clots is lowsomewhere in the range of one in 100,000.

As of early this week Canada had administered roughly2.3 million doses of AstraZeneca. There have been abouta dozen confirmed cases of VITTin the country, includingthree deaths, according to the Public Health Agency of Canada.

AnOxford studyof more than half a million people suggested people are eight to 10 times more likely to get a blood clot as a result ofCOVID-19 infection than because of any vaccine.Thecondition is also treatable.

No regrets

The overriding theme from expertscontinues to be thatAstraZeneca is safe and effective, and the benefits outweigh any risks associated with COVID-19.

"For Manitobans who chose to receive the AstraZeneca vaccine, they did a good thing for themselves, for their families by being protected as early as possible," Reimer said.

WATCH | 'May not have a good use for AstraZeneca going into the future,' Reimer tells Power & Politics:

'We may not have a good use for AstraZeneca going into the future,' doctor says

3 years ago

Duration 1:06

As Manitoba begins to limit its use of AstraZenca, Dr. Joss Reimer, the head of the province's vaccine task force, tells David Common on Power & Politics the province could eventually stop using the vaccine altogether.

Perry has no regrets.

"The real goal is to end this pandemic," she said. "I was and remain primarily interested in doing what is the best for myself andmy family, but also for a wider community that is really in crisis."

The latest advice on AstraZeneca is to wait a minimum of three months before getting a second dose.

"For the overwhelming majority of Manitobans, that's going to be the timeline that best protects them and that's what pharmacies are going to stick to," said Tim Smith with Pharmacists Manitoba.

A pilot project launched days ago sawdoctors and pharmacists givingout Moderna, and Smith said pharmacists want more of those doses soon.

Booking for second-dose appointments for all vaccines is expected to start up no later thanMay 22.

Appointments can be scheduledthrough the province'sonline booking portal, or by calling 1-844-626-8222.

I got AstraZeneca now what?

3 years ago

Duration 2:23

Manitobans who have already received a jab of the AstraZeneca-Oxford vaccine may have a few questions after learning that generally, no more first doses of that vaccine will be offered in the province.